How we changed the way the U.S. government commercializes science: Errol Arkilic — Part 1 of Episode 6 on Sirius XM Channel 111

My guests on Bay Area Ventures on Wharton Business Radio on Sirius XM Channel 111 were:

In my interview with Errol, we discussed the origins of the National Science Foundation Innovation Corps (I-Corps), how and why it was created, and how it changed the way the government commercializes scientific research.

Listen to the full interview by downloading it from SoundCloud here(And download any of the past shows here.)

(Read my interviews with Steve Weinstein and Venk Shukla in a separate post to follow.)


Errol Arkilic was the lead program director for the National Science Foundation I-Corps, which uses my Lean LaunchPad curriculum to teach scientists and engineers how to take their technology out of the lab and into the marketplace. Errol ArkilicToday he is the founder of M34 Capital, a seed capital fund that focuses on early-stage projects being spun out of academic and corporate research labs.

Listen to my entire interview with Errol:

If you can’t hear the clip, click here.

The Origins of National Science Foundation I-Corps
The I-Corps had a serendipitous start. Errol explains in this clip.

Errol: There was a unique opportunity in 2011 when the new director of National Science Foundation said, ‘We want to do something new and different [in helping scientists commercialize their technology].’ … He charged me .. to put together a mentorship program [for academic scientists]. We floated that around the office for about a week and said there was no way that that’s going to work.

We had to do something different. And right about that time you were publishing your notes to the Lean LaunchPad course in spring of 2011, Stanford, E245. … There was a blog post that you wrote … describing the first class at Stanford. I read it and I ran thing down the hall and said to my colleagues, ‘You’ve got to go read this.’ There was one element of the blog post where you described how you were teaching entrepreneurship like we were teaching art. You were going to give them deep lessons of theory and then you were going to dump them in the deep end, so to speak [and give them experiential practice.] That paragraph really resonated with a bunch of us at NSF, me included. 

That was about the same time that Dr. Suresh said we want to do something different. It was a serendipitous moment. …

Steve: …This is the first time I’m hearing the other side of it, … that you actually had a charter .. to do something different. From my side … I wrote the book [The Four Steps to the Epiphany], and while all the theory was in there, you couldn’t just hand somebody the book and expect them to do something. … We needed a way to teach entrepreneurship that was experiential and hands-on.  And much like the educational paradigm, I can tell you about it all the time, but if I actually make you do it, it’s going to stick a lot more.

The Lean LaunchPad class.. was an experiment that no one had ever run before. [Up until then] the capstone class – meaning the best class you could take for being an entrepreneur in a university – was how to write a business plan. Yet we all [anyone teaching who actually had founded a company] knew that in all honesty no business plan survives first contact with customers. But nothing else like [The Lean LaunchPad class] was being taught.  

This [Lean LaunchPad class] was to me a major science experiment – having teams come in, write a business model, talk to 10 customers a week, have them present their results every week and actually be testing a series of of hypotheses.

And the blog you were reading, [was created because] I thought that the class was so crazy and different I … wanted to share what I was doing [with other educators]. And since I open source everything I do, you were the recipient of open source. I have to tell you that everybody who knew me said, ‘Steve these are the most boring blogs you’ll ever write. No one cares about a new class, and no one’s going to ever read them.’ The good news is that for any of you who ever wanted to publish something Errol is a great example of what happens if there is only one person who reads what you write. Something magical could happen.

So that’s when you picked up the phone and called.

Errol: That’s right. I picked up the phone and said, ‘I’ve been reading your blog, I’ve been monitoring E245 and said I’ve got a deal for you. I’ve got 10,000 principal investigators and they all have technologies and projects that they think might have commercial potential, and our job is to figure out a way to figure out whether or not here is. Oh by the way, there’s no funding for you.’

Steve: Thank goodness I was already retired and funding didn’t matter. … My memory of the call is that it kind of went, ‘Hi I’m Errol from the NSF,’ and after I said, ‘What’s the NSF?’ After a long pause and explanation, you said, ‘The U.S. government needs your help,’ and I remember saying, ‘The U.S. government already got my help for four years in Vietnam and they’re not getting it again.’ … I kind of remember there was an even longer pause on your end, as I’m assuming you were thinking, “do I have the right or wrong guy at the end of the phone?”

I was ready to hang up on the call until you said there are 10,000 potential scientists [who could be my students.] In my career, the most fun I ever had was working with and selling to people who were doing truly rocket science. I had to learn what they were doing to be able to understand how to sell to them … [so teaching a class for the NSF] was a new opportunity – could I figure out if we could take rocket scientists and teach them the basics of how to build a business.

Errol: And we did. And I think that the principles of the scientific method applied to the commercial opportunity is spot on. That’s what scientists and engineers needed to embrace.

If you can’t hear the clip, click here

Click on the links below to hear more of Errol’s interview

What made him call Steve?
“A consistent theme we recognized at NSF, was that a lot of the startup companies [we were funding] really weren’t practicing what we knew to be the best and most effective way of taking technologies out of labs. … What we saw were practices that any investor would look at and say there’s got to be a better way of doing it.  And it wasn’t exclusive to the [NSF commercialization] program. It was a crappy way [the U.S. government had] of taking technology out of [all of its] labs.”

If you can’t hear the clip, click here

How I-Corps Teams are Selected
We started the interview process like most people – [we] asked about the idea and the status of the technology was and got spun up on the story. We pretty quickly identified that was the wrong way to go. Because really what we needed were teams that were totally aligned with one another and could work together under extreme pressure and extreme ambiguity because the ideas change anyway. … The teams that are coming together to investigate their commercial opportunity, they need to look way beyond the technical boundaries of their discipline to see if there is a business there. … The key thing is that we’re trying to take teams on a journey with us and with one anther, and some people are not amenable to change and not amenable to coaching and not amenable to advice.

If you can’t hear the clip, click here 

How the I-Corps Has Grown
Errol: The number is up at 550 teams [through the I-Corps classes]. And there’s scale being brought. You and I ran one, we ran two, and then we quickly identified we needed to bring additional Steve Blanks to the table and structure to put in place. We knew we that needed to duplicate the capacity. Stanford loaned us the resources to begin with but we knew that wasn’t in the long term sustainable, so while I was in NSF, we established a program that developed a structure that included a network of academic nodes that teach the course. … We brought on more schools. …

Steve: … If I remember, you and I brought on Georgia Tech, and then University of Michigan and then how many more?

Errol: The group after that is in NY it’s CUNY, NYU and Columbia. In DC it’s George Washington University, the University of Maryland and Virginia Tech, and now Johns Hopkins… in the Bay Area, there’s Berkeley, Stanford and UCSF.  … In Southern California, there’s Caltech, USC and UCLA. And in Texas, it’s the University of Texas at Austin, Rice and …

Steve: We’re losing count, but there’s a bunch of them now that started from that phone call. 550 teams; 20 universities [as nodes and another 36 as sites]; must be 30-40-50 instructors now playing Steve Blank. This kind of makes it one of the largest accelerators in the United States, probably up there with TechStars and Y Combinator except it’s a U.S. government accelerator that takes \ no equity. So, Errol, congratulations, you’ve created something wonderful.

If you can’t hear the clip, click here

Lessons for the Country
I think the strong takeaway is that the commercial considerations must be done in parallel with the technical considerations. It’s not an after thought, it’s not something you come in later and tack on the end. If your goal is to get the technology out of the lab, it’s never too early to start thinking who the customer for that solution is. … If you are a scientist and you think that your science is addressing human needs, you better be talking to some humans. … I think the most rewarding element of the Innovation Corps is when a principle investigator comes back and says, ‘I’m now changing the way I think about crafting my research moving forward.’ That feedback is an incredible demonstration of a significant change.

If you can’t hear the clip, click here

What is M34 Capital?
M34 is a fund that focuses on taking Customer Discovery and the Lean Startup process and applying it in the venture model. We look at companies at their earliest stage of development and we believe with our capital that through the approach of the lean process and customer discovery that we can get companies up the learning curve, up the value curve, more effectively than other approaches.  …  The companies that come out of I-Corps are primed for success but they still need help. That wasn’t surprising to us. We knew that there were gaps that needed to be filled – capital gaps, management gaps, experience gaps and we saw it as an opportunity to get back out and become an entrepreneur again. … We look across the board at any company that has the discipline of customer discovery and Lean and the reason we need that is because it’s just a different way of looking at things. It’s evidence-based, it’s the scientific method and when the company has that on Day Zero, the conversations that we have are just that more meaningful. … If they don’t get it, we’re not touching them. “

If you can’t hear the clip, click here

Listen to the full interview by downloading it from SoundCloud here(And download any of the past shows here.)

One Response

  1. Steve

    This is great – I worked with Errol in the early days of my last start up Geosemble Technologies. He provided some important NSF funding which helped us commercialize our technology which was licensed from the University of Southern California. I got Geosemble funded, we developed and sold the product, and then sold the company in 2012. I’m working now linking up new tech/start up companies with commercial enterprise and government customers. Thanks for this informative piece below


    Andre Doumitt


    310 721 2547

    Los Angeles, CA 90232


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: